姓名:徐东萍
职称:讲师、硕士生导师
电话:024-89383903
电子邮件:18102489307@163.com
教育背景:(从大学起)
2013.09——2017.06 中国医科大学,药物制剂学士学位
2017.09——2022.06 中国医科大学,药理学博士学位
工作经历:(含职称变化)
2022.10——至今 沈阳化工大学,讲师
研究方向:(最多三个)
肿瘤药理学:
非编码RNA、m6A甲基化及小分子化合物的抗肿瘤作用机制
代表性成果:(论文、专利等)
1. Xu D, Wu Y, Wang X, Hu X, Qin W, Li Y, Wang Y, Zhang Z, Lu S, Sun T, Wu Z, Fu D, Fu B, Zhang J, Chen Q, Wei M, Zhao L, Wu H. Identification of functional circRNA/miRNA/mRNA regulatory network for exploring prospective therapy strategy of colorectal cancer. J Cell Biochem. 2020 Mar 1. doi: 10.1002/jcb.29703. Epub ahead of print. PMID: 32115780.
2.Lu S, Han L, Hu X, Sun T, Xu D, Li Y, Chen Q, Yao W, He M, Wang Z, Wu H, Wei M. N6-methyladenosine reader IMP2 stabilizes the ZFAS1/OLA1 axis and activates the Warburg effect: implication in colorectal cancer. J Hematol Oncol. 2021 Nov 7;14(1):188. doi: 10.1186/s13045-021-01204-0. PMID: 34743750; PMCID: PMC8574039.
3. Sun T, Wu Z, Wang X, Wang Y, Hu X, Qin W, Lu S, Xu D, Wu Y, Chen Q, Ding X, Guo H, Li Y, Wang Y, Fu B, Yao W, Wei M, Wu H. LNC942 promoting METTL14-mediated m6A methylation in breast cancer cell proliferation and progression. Oncogene. 2020 Jul;39(31):5358-5372. doi: 10.1038/s41388-020-1338-9. Epub 2020 Jun 23. PMID: 32576970.
4. Wang X, Wu Z, Qin W, Sun T, Lu S, Li Y, Wang Y, Hu X, Xu D, Wu Y, Chen Q, Yao W, Liu M, Wei M, Wu H. Long non-coding RNA ZFAS1 promotes colorectal cancer tumorigenesis and development through DDX21-POLR1B regulatory axis. Aging (Albany NY). 2020 Nov 16;12(22):22656-22687. doi: 10.18632/aging.103875. Epub 2020 Nov 16. PMID: 33202381; PMCID: PMC7746388.
5. Wu H, Li S, Hu X, Qin W, Wang Y, Sun T, Wu Z, Wang X, Lu S, Xu D, Li Y, Guan S, Zhao H, Yao W, Liu M, Wei M. Associations of mRNA expression of DNA repair genes and genetic polymorphisms with cancer risk: a bioinformatics analysis and meta-analysis. J Cancer. 2019 Jun 9;10(16):3593-3607. doi: 10.7150/jca.30975. PMID: 31333776; PMCID: PMC6636297.